Disrupt the defender's timing by varying speed. Change-of-pace is what turns a good handle into a game-effective handle.
Dribble at full speed, then decelerate to a slow walk while staying low, then explode back to full speed. Repeat the slow-fast-slow rhythm down the court.
Full-court trips, 5 slow-fast cycles per trip. 5 trips.
Add a crossover at the acceleration point, then add a defender, then read the defender's reaction to choose the move.